When the 49ers make the short trip down the California coast, they have two chances: slim and none. And none stayed in San Francisco.

The visitors need to win to keep their playoff hopes alive, but must do so without arguably their only consistent offensive weapon, running back Frank Gore. San Diego on the other have only lost once in their six games.

This run is mainly thanks to the superb performances of QB Phillip Rivers. All of Rivers’ numbers are good; his pass completion tops 65%, but possibly the most impressive stat is that seven of his receivers average over 15 yards per catch.

With the Chargers offense in such good shape, their solid defense is under little pressure to make game changing plays, allowing them to sit back and wait for the 49ers inconsistent offense to make a mistake.

San Diego look to be clear favorites heading into this matchup and the bookies tend to agree, valuing them at 2/9, but betting on them to win is still a good bet.